2022 Mercedes-Benz E 350 problems and owner complaints
Explore the records behind recurring owner reports.
Key facts
8 owner complaints analyzed
3 distinct recall campaigns
14,403 mi median reported failure mileage
Scope: 2022 model year. Data snapshot: . 1 complaints include usable failure mileage.
This selection has limited data. It remains available for lookup but is excluded from search indexing.
Most common problems
Unknown Or Other is the most frequently named component, appearing in 3 of 8 complaints (37.5%). A complaint can name multiple components.
| Topic | Matching reports | Share of complaints |
|---|---|---|
| Fuel system concerns | 2 | 25.0% |
| Engine operation | 1 | 12.5% |
Topic matches use published keyword rules. They describe mentions, including negations or comparisons, and do not confirm a diagnosis. Read the matching rules.
Component breakdown
Number of unique complaints naming each component. Top eight shown.
| Category | Count |
|---|---|
| Unknown Or Other | 3 |
| Electrical System | 1 |
| Forward Collision Avoidance: Adaptive Cruise Control | 1 |
| Forward Collision Avoidance: Warnings | 1 |
| Fuel System, Gasoline | 1 |
| Power Train | 1 |
| Vehicle Speed Control | 1 |
| Visibility/Wiper | 1 |
Unknown Or Other: 3; Electrical System: 1; Forward Collision Avoidance: Adaptive Cruise Control: 1; Forward Collision Avoidance: Warnings: 1; Fuel System, Gasoline: 1; Power Train: 1; Vehicle Speed Control: 1; Visibility/Wiper: 1
Reported problems by failure mileage
Complaint counts in mileage bands. These are not failure rates per vehicle or mile.
| Category | Count |
|---|---|
| Under 25,000 | 1 |
| 25,000 to 49,999 | 0 |
| 50,000 to 74,999 | 0 |
| 75,000 to 99,999 | 0 |
| 100,000 to 149,999 | 0 |
| 150,000 and above | 0 |
Under 25,000: 1; 25,000 to 49,999: 0; 50,000 to 74,999: 0; 75,000 to 99,999: 0; 100,000 to 149,999: 0; 150,000 and above: 0
Under 25,000 miles has the most reports with usable mileage (1). 7 complaints have missing, zero or invalid mileage.
Complaints over time
Year the complaint was filed, not the vehicle model year or incident year. The snapshot year is partial.
| Category | Count |
|---|---|
| 2023 | 3 |
| 2024 | 2 |
| 2025 | 1 |
| 2026 | 2 |
2023: 3; 2024: 2; 2025: 1; 2026: 2
Pattern summary
Unknown Or Other leads the component reports. Fuel system concerns appears in 2 complaint narratives. Engine operation appears in 1 complaint narratives. Use these patterns to inspect individual reports and prepare questions for a mechanic.
Calculated from recorded counts. An AI narrative has not been published for this selection.
Complaint evidence
Examples provide context, not a representative sample or a verified diagnosis.
Owner report 11540275 · 2023-08-23 (August 23, 2023)
The contact owns a 2022 Mercedes-Benz E350. The contact stated that on several occasions while driving at various speeds, the vehicle decelerated while the accelerator pedal was depressed. The contact was able to turn off and restart the vehicle. An unknown warning light was illuminated. The vehicle was taken to the dealer where it was diagnosed a fuel pump failure. The contact was informed that the fuel pump needed to be replaced. The vehicle was repaired; however, the contact stated that the following day she smelled a fuel odor coming from t…
Owner-reported narrative. 14,403 miles reported. Look up ODI 11540275 at NHTSA ↗
Owner report 11561167 · 2023-12-20 (December 20, 2023)
My vehicle suddenly stopped in the middle of road. It showed gas tank empty though tank had half tank gas. i would have been hit by a vehicle behind me. Fortunately, there were no vehicles behind me. i filled the remaining half tank , then car started again. I believe that gas sensor was not working. I dropped the vehicle for service to the mercedes benz dealerwith full tank of gas. It was showing empty gas tank and i can drive zero miles. Dealer told me after 3 days that gas tank needs to be replaced. My concern is that , manufacturer might …
Owner-reported narrative. Look up ODI 11561167 at NHTSA ↗
Owner report 11695193 · 2025-10-23 (October 23, 2025)
Major issue found with engine cylinder head in various models with 2.0 Liter Turbo charged engines (Engine code M260 or M264). Cylinder heads have premature wear at valve seats, causing engine misfires and unsafe driving conditions. (Sudden loss of power, even on freeways.) Mercedes-Benz had improved cylinder head design to mitigate this issue, thus proving that they knew it was their product quality that is causing these unsafe issues. Mercedes-Benz even put out a service bulletin to address these defective cylinder heads. This publication…
Owner-reported narrative. Look up ODI 11695193 at NHTSA ↗